COMPUTATIONAL MODELING OF COMPOUNDS THAT INTERACT WITH OPIOID AND CANNABINOID RECEPTORS

Authors

  • Fatima Sapundzhi South-West University “Neofit Rilski”
  • Tatyana Dzimbova South-West University “Neofit Rilski”

DOI:

https://doi.org/10.59957/jctm.v59.i4.2024.17

Keywords:

computational modelling, drug design, structure-activity relationship, opioid receptor, cannabinoid receptor

Abstract

The present study was designed to investigate the structure-activity relationship between cannabinoid and opioid ligands with models of cannabinoid and opioid receptors. There are differences in the mechanisms of pain control for these two types of receptors, but targeting the creation of compounds that bind to both opioid and cannabinoid receptors lead to more effective solving of this problem. This will lead to the development of new and improved strategies to prevent opiate addiction and its consequences.

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Published

2024-07-05

Issue

Section

Articles